Showing posts with label Equipment. Show all posts
Showing posts with label Equipment. Show all posts

Saturday, November 04, 2017

This is a story about success, and what it can do with you

If things go better than expected, plans might have to be changed. In this particular case it was my idea of a relaxed and productive summer time.

As long as the kids are not in school we spend our holidays outside the main summer season. This makes me one of the few lonely workers in the institute during summer break. It is a very relaxed and productive time, since daily disturbances and ad-hoc issues to deal with are reduced to an absolute minimum. The promise is an empty or at least significantly shortened todo list.

In the past years, summer time was always my opportunity to catch up with the fast-paced year and get well prepared for the second half. And so I expected it to be also in 2017. However, it came differently.

End of July, just after having finished our four-weeks master‘s practical, we were contacted by the coordinator of the project Dream Resource, where we are participating for Green Toxicology. Other than expected the project partners already successfully synthesised a set of promising substances. And they planned to disseminate their results at a conference mid October. However, the concept behind this synthesis is unique and very innovative. It should be patented, and the application had to be filed before the idea got shared with the community. What they were lacking, however, was proof of ready biodegradability. Deadline 28 September.

It was our task to do these experiments, and we knew this of course. But we weren't prepared to start the investigation in that very moment or even the next two weeks. We first had to buy the equipment and material. Now, for this scale of a biodegradability study we required purchase of equipment worth several thousands of Euros. And here the difficulties started.

As a university scientist you cannot just go to a retail store or on amazon and get whatever you like. There are certain rules attached to procurement. And in Germany they are especially strict if the amount of money to be spend exceeds EUR 5000. But procurement is not a fast process, it involves asking for competing quotes and ordering via central procurement of the university. These guys have way more to handle than that one application you are handing in. It ends up in a pile with the other applications, which is processed in order of receipt. Also, it doesn't help to label your application "urgent", since literally all of them are.

Now, the only way around this was to find a device for biodegradability studies that came at a price below this threshold. We luckily did so: two Hach BOD direct plus. And we could order them much faster than if going via central procurement. But then the supplier didn't have the devices on stock. So they organised that the next two units coming freshly out of manufacturing will immediately be delivered to them. They then processed our order with highest priority (in business this can be a working concept) and we received them just one day before we had to start the experiment to be able to run it for 28 days, as required by the OECD Guideline 301 Method F; which is one standardised procedure for such investigations.

The results we produced were what we hoped to see. Those novel substances are far better biodegradable than their conventional counterparts. The patent application got filed in time and the project partners could present their work at the conference without omitting central parts that might have otherwise harmed the patent.

So a full success! My summer time, however, was gone. Spent searching for suitable equipment, talking on the phone, comparing prices, writing emails, planning the experiment, and hoping that everything will work out in the one or the other way. It was an emotional rollercoaster, with one day good news, the other day bad news, one day hope and the other day resignation...and then hope again.

But we helped innovation, and since biodegradability of chemicals is an important aspect for the environment, we might have contributed to quality of life - if these substance are eventually substituting the conventional compounds. That's a good feeling, despite the lost summer time.

Saturday, February 22, 2014

1st Biological AdVent in-house exhibiton

On 12 December 2013 we opened doors for the 1st Biological Advent in-house exhibition in the framework of the academia-industry cooperation Students Lab "Fascinating Environment".

This event allowed all of our industry partners to present not only their contributions to the lab's equipment but also other products from their portfolio. The audience consisted of colleagues from other biological institutes as well as many interested students.

We could welcome nearly all of our partners: Nikon Instruments, Tecan, Hettich, Büchi, Memmert, Prior Scientific, Integra Biosciences, Promega, BFI Optilas, Mettler Toledo. All representants were pleased with how the exhibition went and showed interest to repeat it.

In the past we had already one "Industry Day 2010", but the following years we found no capacities to organise a second event. With the date fixed to the time before Christmas we want to make this exhibition an annual activity. Next round will also have useful lectures by our partners, e.g., on the very basics of microscopy, weighing practice, functioning of a monochromator and the like.

As a sideeffect, I had another opportunity to create a logo.

Friday, September 06, 2013

Micronucleus assay goes robotics

In future our micronucleus assay (MNC) will run semi-automatically using a slideloader and a software-controlled automatic stage attached to a fluorescence microscope with a camera. Together with Nikon GmbH and Prior Scientific Instruments GmbH we successfully tested this combination as a measure for a dramatic increase in sample throughput of the MNC. Furthermore this allows to have well documented MNC results. For several cell types also a software-based evaluation should be feasible.

The equipment is the most recent addition to the high-end technology facilities in our Students Lab Fascinating Environment. Nikon as well as Prior are partners of this fruitful academia-industry initiative. We also produced a movie clip showing the equipment at work. I will link it here soon.